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DTI-ALPS based findings post subacute TBI support a correlation between disease severity based on blood levels of neurofilament light protein (NfL), a highly sensitive TBI biomarker, and glymphatic system disruption (Butler et al., 2023)

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(Cell Metabolism, 2018) demonstrated that under metabolic stress such as glucose restriction, MOTS-C translocates from its extranuclear pool into the nucleus, co-precipitates with NRF2, and binds antioxidant response element (ARE) sequences to regulate stress-adaptive nuclear gene expression